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Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation

✍ Scribed by K. Liaras; A. Geronikaki; J. Glamočlija; A. Ćirić; M. Soković


Book ID
108073016
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
250 KB
Volume
19
Category
Article
ISSN
0968-0896

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Piperidine-mediated synthesis of thiazol
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## Abstract A series of new thiazolyl chalcones, 1‐[2‐amino‐4‐methyl‐1, 3‐thiazol‐5‐yl]‐3‐aryl‐prop‐2‐en‐1‐one were prepared by piperidine mediated Claisen‐Schmidt condensation of thiazolyl ketone with substituted aromatic aldehyde. These chalcones on cyclization gave 2‐amino‐6‐(2‐amino‐4‐methyl‐1,