Synthesis and evaluation of new chalcones, derived pyrazoline and cyclohexenone derivatives as potent antimicrobial, antitubercular and antileishmanial agents
โ Scribed by Monga, Vikramdeep; Goyal, Kamya; Steindel, Mario; Malhotra, Manav; Rajani, Dhanji P.; Rajani, Smita D.
- Book ID
- 121555371
- Publisher
- Springer-Verlag
- Year
- 2013
- Tongue
- English
- Weight
- 344 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1054-2523
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๐ SIMILAR VOLUMES
## Abstract Some of the title compounds, especially derivatives having two halogenโsubstituents, show better antimicrobial activity than the standard penicillin.
## Abstract A series of new thiazolyl chalcones, 1โ[2โaminoโ4โmethylโ1, 3โthiazolโ5โyl]โ3โarylโpropโ2โenโ1โone were prepared by piperidine mediated ClaisenโSchmidt condensation of thiazolyl ketone with substituted aromatic aldehyde. These chalcones on cyclization gave 2โaminoโ6โ(2โaminoโ4โmethylโ1,