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Synthesis and biological evaluation of naphthalene, furan and pyrrole based chalcones as cytotoxic and antimicrobial agents

✍ Scribed by Abhishek Budhiraja, Kanika Kadian, Mandeep Kaur, Vikas Aggarwal, Atul Garg, Sameer Sapra, Kunal Nepali, O. P. Suri, K. L. Dhar

Book ID: 115530925
Publisher: Springer-Verlag
Year: 2011
Tongue: English
Weight: 295 KB
Volume: 21
Category: Article
ISSN: 1054-2523
DOI: 10.1007/s00044-011-9733-y

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## Abstract In order to evaluate the anti‐hyperlipidemic effect of synthetic chalcones and some analogues, nineteen compounds with different substituents in both rings were synthesized and hypolipidemic activities were measured __in vivo__ using Triton WR1339 acute and hypercaloric chronic assays.