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Therapy-related, mixed phenotype acute leukemia with t(1;21)(p36;q22) and RUNX1 rearrangement

✍ Scribed by Katsuya Yamamoto; Akiko Sada; Yuko Kawano; Yoshio Katayama; Manabu Shimoyama; Toshimitsu Matsui

Book ID
113513779
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
634 KB
Volume
201
Category
Article
ISSN
0165-4608

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## Abstract The t(1;21)(p36;q22) is a recurrent chromosome abnormality associated with therapy‐related acute myeloid leukemia (AML). Although involvement of __RUNX1__ has been detected by fluorescence in situ hybridization analysis, the partner gene has not been reported previously. We identified a