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Identification of truncated RUNX1 and RUNX1-PRDM16 fusion transcripts in a case of t(1;21)(p36;q22)-positive therapy-related AML

✍ Scribed by Stevens-Kroef, M-J P L; Schoenmakers, E F P M; van Kraaij, M; Huys, E; Vermeulen, S; van der Reijden, B; van Kessel, A Geurts


Book ID
110056729
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
126 KB
Volume
20
Category
Article
ISSN
0887-6924

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## Abstract The t(1;21)(p36;q22) is a recurrent chromosome abnormality associated with therapy‐related acute myeloid leukemia (AML). Although involvement of __RUNX1__ has been detected by fluorescence in situ hybridization analysis, the partner gene has not been reported previously. We identified a