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CLCA2, a novel RUNX1 partner gene in a therapy-related leukemia with t(1;21)(p22;q22)

✍ Scribed by Amélie Giguère; Josée Hébert


Book ID
113513913
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
517 KB
Volume
202
Category
Article
ISSN
0165-4608

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## Abstract The t(1;21)(p36;q22) is a recurrent chromosome abnormality associated with therapy‐related acute myeloid leukemia (AML). Although involvement of __RUNX1__ has been detected by fluorescence in situ hybridization analysis, the partner gene has not been reported previously. We identified a