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Acute myeloid leukemia (M2) with a cryptic RUNX1/RUNX1T1 t(1;21;8)(p36;q22;q22) variant

✍ Scribed by Carlos A. Tirado; Weina Chen; Federico J. Valdez; Samuel Henderson; Jeff Doolittle; Rolando Garcia; Sangeeta Patel; Scott Holdridge; Candace Chastain; Robert H. Collins


Book ID
113513537
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
177 KB
Volume
193
Category
Article
ISSN
0165-4608

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## Abstract The t(1;21)(p36;q22) is a recurrent chromosome abnormality associated with therapy‐related acute myeloid leukemia (AML). Although involvement of __RUNX1__ has been detected by fluorescence in situ hybridization analysis, the partner gene has not been reported previously. We identified a