Thein vivometabolism of 5-(4-nitrophenyl)-4-(2-phenylethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione in rats
✍ Scribed by E. E. Oruç; L. Kabasakal; S. Rollas
- Publisher
- Springer-Verlag
- Year
- 2003
- Tongue
- English
- Weight
- 582 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0378-7966
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In the title compound, C 18 H 15 OPÁC 10 H 12 N 4 OS, the triazole ring makes a dihedral angle of 51.24 (7) with the attached benzene ring. The triazole ring and its thione substituent are delocalized. There are intermolecular N-HÁ Á ÁO and N-HÁ Á ÁS hydrogen bonds, which also involve the cocrystall
## Abstract magnified image Various 4‐amino‐2,3‐dihydro‐4__H__‐triazoles with aromatic, aliphatic and heterocyclic substituents at the C(5) position were synthesized from corresponding esters and thiocarbohydrazide. This method allows the synthesis these heterocycles in a short time and at reduced
The acyclic C=N double bond of the title compound, C~10~H~10~N~4~S, is __trans__ configured. The molecule is almost planar. The angle between the two rings is just 10.25 (7)°. The crystal packing is stabilized by N—H...S hydrogen bonds and π–π interactions.