Convenient way to 5-substituted 4-amino-2,3-dihydro-4H-1,2,4-triazole-3-thiones
✍ Scribed by Romualdas Smičius; Milda Malvina Burbuliene; Virginija Jakubkienė; Emilija Udrwėnaitė; Povilas Vainilavičius
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2007
- Tongue
- English
- Weight
- 362 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
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Various 4‐amino‐2,3‐dihydro‐4__H__‐triazoles with aromatic, aliphatic and heterocyclic substituents at the C(5) position were synthesized from corresponding esters and thiocarbohydrazide. This method allows the synthesis these heterocycles in a short time and at reduced expenses.
📜 SIMILAR VOLUMES
**Synthesis of 4‐Amino‐2‐aryl‐2,4‐dihydro‐3__H__‐1,2,4‐triazol‐3‐onen** The title compounds **10** are prepared in a multistep reaction sequence starting with alkyl 2‐arylhydrazono‐2‐chloracetates **3** and aldehyde hydrazones **4.**
A series of 4-(alkylidene/arylidene)amino-5-(2-furanyl)-2.4-dihydro-3H-I .2.4-triazolc-3-1hiones (2) and 6-aryl-3-(2-furanyl)-7H-12.4-triazolo[3,4-b]( 1.3.41 thiadiazines (3) werc synthesized. The configuration of 2g was assigned on che basis of 'H-NMR data. Of the new derivatives tesced. only 2b. 2