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The α-Effect in the Stereochemistry of Kinetic Ketonization of Enols 1,2

✍ Scribed by Zimmerman, Howard E.; Wang, Pengfei


Book ID
127216672
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
136 KB
Volume
68
Category
Article
ISSN
0022-3263

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Influence of enolate geometry on the ste
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Preformed lithium enolates of ketones react with acyclic a,p-unsaturated ketones to give 1,5-diketones in good chemical yields. A strong correlation exists between enolate geometry and product stereochemistry; enolates having the z configuration provide anti addition products while E enolates usua