Kinetic protonation of enols, enolates, and analogs. The stereochemistry of ketonization
โ Scribed by Zimmerman, Howard E.
- Book ID
- 120475303
- Publisher
- American Chemical Society
- Year
- 1987
- Tongue
- English
- Weight
- 687 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0001-4842
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Preformed lithium enolates of ketones react with acyclic a,p-unsaturated ketones to give 1,5-diketones in good chemical yields. A strong correlation exists between enolate geometry and product stereochemistry; enolates having the z configuration provide anti addition products while E enolates usua