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The urokinase plasminogen activator system in cancer: Implications for tumor angiogenesis and metastasis

✍ Scribed by Andrew P. Mazar; Jack Henkin; Ronald H. Goldfarb

Book ID
110272859
Publisher
Springer
Year
1999
Tongue
English
Weight
254 KB
Volume
3
Category
Article
ISSN
0969-6970

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The urokinase-type plasminogen activator (u-PA) system consists of the serine proteinases plasmin and u-PA; the serpin inhibitors a 2 -anti-plasmin, PAI-1 and PAI-2; and the u-PA receptor (u-PAR). Two lines of evidence have strongly suggested an important and apparently causal role for the u-PA syst