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The Urokinase-type Plasminogen Activator System in Prostate Cancer Metastasis

✍ Scribed by Shijie Sheng

Book ID
110337803
Publisher
Springer
Year
2001
Tongue
English
Weight
69 KB
Volume
20
Category
Article
ISSN
0167-7659

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The urokinase-type plasminogen activator
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The urokinase-type plasminogen activator (u-PA) system consists of the serine proteinases plasmin and u-PA; the serpin inhibitors a 2 -anti-plasmin, PAI-1 and PAI-2; and the u-PA receptor (u-PAR). Two lines of evidence have strongly suggested an important and apparently causal role for the u-PA syst