𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The total synthesis of 12-HETE (12-hydroxyeicosatetraenoic acid) and 12,20-diHETE

✍ Scribed by Leblanc, Yves; Fitzsimmons, Brian J.; Adams, Julian; Perez, Francoise; Rokach, Joshua

Book ID
125941492
Publisher
American Chemical Society
Year
1986
Tongue
English
Weight
790 KB
Volume
51
Category
Article
ISSN
0022-3263

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Enantiospecific total synthesis of 8- an
Enantiospecific total synthesis of 8- and 12-hydroxyeicosatetraenoic acid
✍ Pendri Yadagiri; Sun Lumin; Paul Hosset; Jorge Capdevila; J.R Falck πŸ“‚ Article πŸ“… 1986 πŸ› Elsevier Science 🌐 French βš– 135 KB

The R-and S-isomers of 8-and 12-hydroxyeicosatetraenoic acid (8-and lP-HETE) were synthesized from dimethyl malate derived precursors.

Total synthesis of (11R, 12S)-diHETE
Total synthesis of (11R, 12S)-diHETE
✍ AgnΓ¨s Gigou; Jean-Pierre Beaucourt; Jean-Paul Lellouche; RenΓ© Gree πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science 🌐 French βš– 205 KB

The first total synthesis of (1 lR, 12s) diHETE IS reported. The key step is the highly chemioand stereaselective osmylation of a double bond in a trienyne system selectively complexed by an Fe(CO)3 group.

Total enantiospecific synthesis of 12(r)
Total enantiospecific synthesis of 12(r)-hete
✍ Ira M. Taffer; Robert E. Zipkin πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 French βš– 116 KB

All chemical yields refer to chromatographically homogeneous products. All new compounds exibited satisfactory spectral (IR, NMR, and mass ) data.