The synthesis of polyhydroxylated amino acids from glucuronolactone: enantiospecific syntheses of 2s, 3r, 4r, 5s-trihydroxypipecolic acid, 2r, 3r, 4r, 5s-trihydroxypipecolic acid and 2r, 3r, 4r-dihydroxyproline
β Scribed by Bharat P. Bashyal; Hak-Fun Chow; Linda E. Fellows; George W.J. Fleet
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- French
- Weight
- 643 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
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Taking advantage of the high functionality of an enantiopure protected syn-2R-amino-l,3,4-triol derivative, easily available on a multigram scale from Disoascorbic acid, several biologically active compounds have been synthesized such as the (2S,3R)-3-amino-2-hydroxydecanoic acid (AHDA), the N-termi