Synthesis of 2R,3S,4R-dihydroxyproline from D-ribonolactone
β Scribed by J.C. Dho; G.W.J. Fleet; J.M. Peach; K. Prout; P.W. Smith
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- French
- Weight
- 140 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0040-4039
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Taking advantage of the high functionality of an enantiopure protected syn-2R-amino-l,3,4-triol derivative, easily available on a multigram scale from Disoascorbic acid, several biologically active compounds have been synthesized such as the (2S,3R)-3-amino-2-hydroxydecanoic acid (AHDA), the N-termi