The synthesis of l-alkyl-1,4-dihydro-4-quinolone-2-carboxylic acids
✍ Scribed by H. Cairns; A. R. Payne
- Book ID
- 112125315
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1978
- Tongue
- English
- Weight
- 243 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0022-152X
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📜 SIMILAR VOLUMES
## Abstract A modification of the Gould‐Jacobs reaction, particularly useful for the preparation of N‐alkyl‐4‐quinolone‐3‐carboxylic acids, is described. Decarboxylation of these acids leads to N‐alkyl‐4‐quinolones or, in the case of N‐ethyl‐benzo[h]‐4‐quinolone‐3‐carboxylic acid, to 4‐ethoxy‐benzo
## Abstract The reaction of the alkylhydrazinoquinoxaline __N__‐oxides **2a‐d** with dimethyl acetylenedicarboxylate gave the dimethyl 1‐alkyl‐1,5‐dihydropyridazino[3,4‐__b__]qumoxaline‐3,4‐dicarboxylates **3a‐d**, whose reaction with nitrous acid effected the C~4~‐oxidation to afford the dimethyl