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The Synthesis and Some Reactions of N-Alkyl-4-Quinolone-3-Carboxylic Acids

✍ Scribed by D. G. Markees; Linda S. Schwab

Publisher
John Wiley and Sons
Year
1972
Tongue
German
Weight
489 KB
Volume
55
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

A modification of the Gould‐Jacobs reaction, particularly useful for the preparation of N‐alkyl‐4‐quinolone‐3‐carboxylic acids, is described. Decarboxylation of these acids leads to N‐alkyl‐4‐quinolones or, in the case of N‐ethyl‐benzo[h]‐4‐quinolone‐3‐carboxylic acid, to 4‐ethoxy‐benzo[h]quinoline. Evidence for the structure of the products is presented and the synthesis of relevant compounds is described.

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