✦ LIBER ✦

The synthesis of glycine receptor radioligands [21, 22-3H] dihydrostrychnine and [2-3H] strychnine at high specific activity

✍ Scribed by Crist N. Filer; David G. Ahern

Publisher: John Wiley and Sons
Year: 1989
Tongue: French
Weight: 351 KB
Volume: 27
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580270309

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The preparation and characterization of

The preparation and characterization of [3H] histamine.2HCl at high specific activity1

✍ Crist N. Filer; David G. Ahern 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 292 KB

Synthesis and characterization of the po

Synthesis and characterization of the potent cannabinoid agonist [naphthyl-3H] WIN 55212-2 at high specific activity

✍ Richard J. Seguin; Crist N. Filer 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 79 KB

## Abstract [Naphthyl‐^3^H] WIN 55212‐2 was prepared at high specific activity by the catalytic tritiation of dibromo precursor **3**. Product **4** was characterized by chromatography as well as tritium NMR and proven to be a useful radioligand. Copyright © 2002 John Wiley & Sons, Ltd.

Synthesis of the 3H-labelled 5-HT3 antag

Synthesis of the 3H-labelled 5-HT3 antagonist (RS-25259-197) at high specific activity

✍ Leyi Gong; Howard Parnes 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 415 KB 👁 1 views

The preparation of the title compound, a selective 5-HT, antagonist with anti-emetic properties, is described. The key intermediate involved is 6-bromo-1,2-dihydronaphthoic acid (s), which was synthesized from 4-bromophenylacetic acid by Micheal addition, acid-induced ring cyclization, reduction and

Synthesis of high specific activity (3,4

Synthesis of high specific activity (3,4-[3H]cyclohexyl)-N-[1 (2-benzo[b]thienyl)cyclohexyl]piperidine {[3H]BTCP}: A selective probe for the dopamine-reuptake complex

✍ Brian R. de Costa 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 455 KB 👁 1 views

High specific activity [3H]BTCP, a radioligand for the dopaminereuptake complex was synthesized in 7-steps starting with the readily available starting materials, cyclohexane-l,4-dione monoethylene ketal and benzo[b]thiophene; the tritium label was introduced in the final step on the 3-and 4-positio

The novel synthesis of the protease inhi

The novel synthesis of the protease inhibitor (S)-1-chloro-3-[(p-tolylsulfonyl)amino]-7-amino-2-[5,5,6,6-3H]heptanone ([3H]TLCK) labeled to high specific activity with tritium

✍ A. J. Villani; J. R. Heys 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 466 KB 👁 2 views

An expedient synthesis of high specific

An expedient synthesis of high specific activity tritium labelled 4-fluoro-1-[1-(2-thienyl)]cyclohexylpiperidine ([3H]FTCP), a ligand for further characterization of the phencyclidine/NMDA receptor complex

✍ Neile A. Grayson; Brian R. de Costa; Joannes T. M. Linders; Kenner C. Rice 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 319 KB 👁 1 views

## Abstract [^18^F]4‐Fluoro‐1‐[1‐(2‐thienyl)cyclohexyl)]piperidine is a ligand potentially useful for positron emission tomography of the PCP/NMDA receptor complex in the mammalian brain. The tritium‐labelled title compound was synthesized in 5 steps starting with cyclohexanone. Catalytic tritiolys