## Abstract The synthesis of indole‐3‐acetyl‐2‐^14^C‐N‐aspartic acid from carrier‐free indole‐3‐acetic acid‐2‐^14^C (54.5 mCi/mmole) and bis‐t‐butyl‐l‐aspartic acid was accomplished by coupling with dicyclohexylcarbodiimide followed by removal of the ester blocking groups by treatment with 2 N NaOH
The synthesis of E-β-[2-14C] indol-3-ylacrylic acid
✍ Scribed by H. Morrison; Taj Mohammad; B. Severns
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- French
- Weight
- 219 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A general method for microscale synthesis of ^14^C‐labeled indole‐3‐acetic acids with halogen substitutions in the benzene ring is described. The method utilizes halogen substituted phenylhydrazines reacted with [^14^C]‐2‐oxoglutarate to generate the halogenated indole‐3‐acetic acid. 3‐
## Abstract 2,3‐Bis(p‐methoxyphenyl)indole‐2‐^14^C was prepared at a specific activity of 1.71 mCi/mM from Ba^14^CO~3~ by a 4‐step synthetic sequence in 23% overall radiochemical yield.
## Abstract 2,3‐Dihydroxybenzoic acid‐(carboxyl‐^14^C) can be synthesized in high overall yield from commercially‐available 2,3‐dimethoxybenzoic acid. The synthetic route features the application of a Curtius rearrangement, the thermal decomposition of a carboxylic acid azide to an isocyanate. The
Specifically labelled phenylacetic acid and mandelic acid derivatives, metabolites of L-Dopa, have been synthesized via the intermediary labelled benzyl alcohols, which were prepared by reduction of the methyl esters of the appropriate benzoic acids. The benzyl alcohols have been converted to the co