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Synthesis of 2,3-dihydroxybenzoic acid - (carboxyl-14C)

✍ Scribed by M. G. Sundaram

Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
194 KB
Volume
18
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

2,3‐Dihydroxybenzoic acid‐(carboxyl‐^14^C) can be synthesized in high overall yield from commercially‐available 2,3‐dimethoxybenzoic acid. The synthetic route features the application of a Curtius rearrangement, the thermal decomposition of a carboxylic acid azide to an isocyanate. The method is suitable for the preparation of the title compound on both micro and semimicro scales.

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