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The synthesis of deuterium labelled mono-hydroxy metabolites of phenytoin

✍ Scribed by John A Hoskins

Publisher: John Wiley and Sons
Year: 1984
Tongue: French
Weight: 408 KB
Volume: 21
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580210709

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✦ Synopsis

Abstract

The synthesis of the 3‐hydroxyphenyl and 4‐hydroxyphenyl metabolites of 5,5‐diphenylhydantoin (Phenytoin) labelled with deuterium in either of the two phenyl rings and 5(4‐hydroxy‐[^2^H~4~]phenyl)‐5‐[^2^H~5~] phenylhydantion is described.

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