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The synthesis of conformationally/rotationally restricted analogs of the neurotransmitter serotonin

โœ Scribed by John E. Macor; David H. Blank; Ronald J. Post


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
293 KB
Volume
35
Category
Article
ISSN
0040-4039

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Synthesis of a novel, conformationally r
โœ Luca Franceschetti; Aaron Garzon-Aburbeh; Mahmoud R. Mahmoud; Benedetto Natalini ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 242 KB

Abslrart: The synthesis of a new, conformationally restrained a~log of tryptoghan, 1,2,3,4ktrahydtv-2-ami-2-mrboxy\_cyflopentfbJindole (5) is descrhd. The key step involzm the BF3-Et,0 catalyzed intramolecular cycl&atian of adinoketone 2b into the lt3,4tetrahydro\_~~ (3). Conformationally restricted