Synthesis of a dihydropyrano[3,2-e]indole as a rotationally restricted phenolic analog of the neurotransmitter serotonin
β Scribed by John E. Macor; Michael E. Newman
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 288 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
## Abstract The use on a gold catalyst facilitates the Claisen rearrangement/cyclization of propargyloxyindoles (I) allowing to reduce the reaction temperature from 156Β°C to 101Β°C with better yields of the condensed heterocycles (II).
Evidence for a Stepwise Ionic Pathway in the Generation of Indole-2,3-quinodimethanes. -A strategy employing C-2 carbon substitution of (I) by NBS bromination is used for an effective synthesis of the lactone (IV). However, contrary to the previously reported analogues (V) compound (IV) is totally
## Abstract For Abstract see ChemInform Abstract in Full Text.