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Synthesis and biological activity of conformationally restricted tricyclic analogs of the hormone melatonin

✍ Scribed by V. Leclerc; P. Depreux; D. Lesieur; D.H. Caignard; P. Renard; P. Delagrange; B. Guardiola-Lemaitre; P. Morgan


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
248 KB
Volume
6
Category
Article
ISSN
0960-894X

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Enantioselective Synthesis of 2-(2-Arylc
✍ Ayhanβ€…S. Demir; Γ–zge Sesenoglu; Dincer ÜlkΓΌ; Cengiz Arici πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 German βš– 199 KB

## Abstract Starting from simple aromatic aldehydes and acetylfuran, (__E__)‐1‐(furan‐2‐yl)‐3‐arylprop‐2‐en‐1‐ones (**2**) were synthesized in high yields. Cyclopropanation of the Cο£ΎC bond with trimethylsulfoxonium iodide (Me~3~SO^+^I^βˆ’^) furnished (furan‐2‐yl)(2‐arylcyclopropyl)methanones **3** in