## Abstract α‐Methylstyrenes with all three side chain carbons specifically ^14^C‐labelled have been synthesised by Wittig reactions between the appropriately labelled acetophenones or methylene triphenylphosphoranes. The yields in all cases were good and any radiochemical impurities could be readi
The synthesis of 14C-safrole, myristicin and elemicin labeled in the allyl side chain
✍ Scribed by M. Walker; J. McKinney; E. Oswald
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- French
- Weight
- 213 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
The preparation of 1‐[ (3′‐^14^C)‐Allyl]‐3,4‐methylene dioxy‐,1‐[(3′‐^14^C)‐allyl]‐3‐methoxy‐4,5‐methylene dioxy‐, and 1‐[(3′‐^14^C)‐allyl]‐3,4,5‐trimethaoxy benzenes is described. The ^14^C‐label was introduced into the 3′‐carbon of the allylic side chain via the Wittig reaction.
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y-2H2]Estragole was synthesized [ methylene-112] -benzyl chloride; [ p-2H] estragole via reduction vinylation of 4-methoxy-2 of 3-(~-anisyl)-propyne with bis-3-methyl-2-butylborane (obtained from LiAl H4 , BF3 etherate and 2-methyl-2-butene) ; k-2H]estragole 2 ? y & cinnamaldehyde with NaBH3CN.
## Abstract The ring‐ and side‐chain‐^14^C‐labeled DL‐4,4′‐propylenedi‐2,6‐piperazinediones (I) were synthesized from chloroacetic acid‐1‐^14^C in two steps and from DL‐analine‐1‐^14^C in six steps, respectively. The radiochemical yield for the ring labeling was 24.5%; for the side‐chain labeling i
Ortho-and para-f luoro-a-methylstyrenes specifically 14C-labelled in all three positionsof the side chain have been synthesized by a modified Wittig reaction. synthesized as intermediates. The yields in all cases were good and any radiochemical impurities could be readily removed by careful fraction
## Abstract 1‐Nitro‐9/dimethylaminopropylamino/‐acridine dihydro‐chloride /C‐283, ‘Ledaarin’/ is used as an anti‐twnor drug, In view of the studies on its mechanism of action. the syntheses of two specimens of this compound labelled with radioisotopes have been carried out. One of them contained C^
## Abstract Methylation under pressure of o‐allyloxyphenol with ^14^C‐metheyl iodide was successfully used for the synthesis of ^14^C‐eugenol and isoeugenol labeled in the methoxy position. Eugenol and isoeugenol are important compounds in the practice of dentistry.