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The synthesis of 14C-labelled (U) 2,4,2′,4′-tetrachlorobiphenyl

✍ Scribed by B. Melvas

Publisher
John Wiley and Sons
Year
1974
Tongue
French
Weight
351 KB
Volume
10
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

It was possible to prepare ^14^C‐2,4,2′,4′‐tetrachlorobiphenyl with a purity of 98% by condensation of ^14^C‐1‐chloro‐2,4‐dinitro‐benzene to yield ^14^C‐2,4,2′,4′,‐tetranitrobiphenyl and substitution of the nitro groups by chlorine with thionyl chloride. The synthesis must be carried out on a small scale for two reasons‐the cost and the hazards with radioactive material. The synthesis described here was performed on a 10mg scale. Both of the chemical reactions were performed in sealed ampoules and the overall yield varied between 30 and 40%.

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