𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The synthesis of [14C] -labelled haloperidol and [d4]-and [d8] haloperidol

✍ Scribed by I. Fellows; T. A. Harrow; R. Honeyman

Publisher
John Wiley and Sons
Year
1979
Tongue
French
Weight
426 KB
Volume
16
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis

The s y n t h e s i s o f [ 14C

] h a l o p e r i d o l f o r use i n metabolism s t u d i e s , and t h e s y n t h e s i s o f [ d4]-and[d8] h a l o p e r i d o l f o r use i n b i o a v a i l a b i l i t y s t u d i e s , i s d e s c r i b e d .

πŸ“œ SIMILAR VOLUMES

Labelling of neuroleptic butyrophenones.
Labelling of neuroleptic butyrophenones. 1. syntheses of haloperidol-14C and trifluperidol-14C
✍ Iwao Nakatsuka; Kazuo Kawahara; Takeshi Kamada; Akira Yoshitake πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 French βš– 316 KB

## 4-[4-(4-Chlorophen y l ) -4-hydroxypiperidinol -4 ' -f l u o r o b u t y r op h e n o n e ( h a l o p e r i d o l ) ( I ) and 4'-fluoro-4-[4-hydroxy-4-(3-trif 1 u o r o m e t h y l p h e n y l ) p i p e r i d i n o l b u t y r o p h e n o n e ( t r i f 1 u p e r i d o f ) (11) , n e u r o l e p t

Synthesis of 14C-labelled methylglyoxal
Synthesis of 14C-labelled methylglyoxal and S-D-lactoylglutathione
✍ James D. Clelland; Paul J. Thornalley πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 French βš– 336 KB

## Abstract [2‐^14^C]Methylglyoxal and S‐D‐[2‐^14^C]lactoylglutathione were synthesised from [2‐^14^C]acetone. Acetone was oxidised to methylglyoxal by selenium dioxide and was purified by distillation (yield: 23% based on acetone). Methylglyoxal was converted to S‐D‐lactoylglutathione by reaction

Synthesis and characterization of carbon
Synthesis and characterization of carbon-14 labelled 4, 4β€²- diaminodiphenyl sulfone (dapsone-14C; DDS-14C)
✍ C. E. Blackburn; A. J. Glazko πŸ“‚ Article πŸ“… 1972 πŸ› John Wiley and Sons 🌐 French βš– 206 KB πŸ‘ 1 views

## SYNTtIESIS AHD CHARACTERIZATION OF CARBON-14 LABELLED 4,4'-DIAMINODIPHENYL SULFONE (DAPSONE-l4C; D 3 S -1 4 C > , C.E. B l a c k b u r n and A.J. G l a z k o . D e p a r t m e n t o f P h a r m a c o l o g y . D i v i s i o n of S c i e n t i f i c and M e d i c a l Affairs. P a r k e -D a v i

Synthesis [4-14C]- and [6,7-D2]trilostan
Synthesis [4-14C]- and [6,7-D2]trilostane
✍ D. Jonston; D. Elder πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 French βš– 295 KB

## SLmrarY A synthetic procedure for producing [6.7-d2]trilostane is described. The synthesis was accomplished in 6 steps from androsta-4,6-dien-3,17-dione with the label being introduced by catalytic deuteration. The synthetic procedure, using [4-14Cltestosterone, gave the required ~d ~~l t r i ~