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The synthesis of 11-substituted prostaglandin intermediates

✍ Scribed by Kenji Inoue; Kiyoshi Sakai

Publisher
Elsevier Science
Year
1977
Tongue
French
Weight
190 KB
Volume
18
Category
Article
ISSN
0040-4039

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✦ Synopsis

In a previous paper, 2) we reported a convenient synthetic method for lldeoxy prostaglandin intermediates.

In connection with this method, we are further interested in the preparation of ll-substituted prostaglandins by Wittig reaction of a-dienols with stable ylides. Now we wish to report the synthesis of llhydroxymethyl PGs I, 3) ll-amino PGs 2 4) and natural PGs 3 5) synthetic intermediates which correspond to the Corey's intermediate.

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