๐”– Bobbio Scriptorium
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The synthesis and antiviral properties of (E)-5-(2-bromovinyl)-2'-deoxyuridine-related compounds

โœ Scribed by Mark Ashwell; A.Stanley Jones; Ajit Kumar; Jon R. Sayers; Richard T. Walker; Takashi Sakuma; Erik De Clercq


Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
603 KB
Volume
43
Category
Article
ISSN
0040-4020

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Abstra& 5-Btcmoethynylmcil and its deoxyriboside cau be prepared io good yields starting from dibromovinyluracil, which is accesible by litfmtm mehds. S-Btumaethynyl-deox~ is less eikxive against HSV-1 than E-~cwitty0-deox~ but, similar to BVDU, seems to exhibit a certain nelectivity toward HSV-1. M