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The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation

✍ Scribed by Gresh, Lionel; Bourachot, Brigitte; Reimann, Andreas; Guigas, Bruno; Fiette, Laurence; Garbay, Serge; Muchardt, Christian; Hue, Louis; Pontoglio, Marco; Yaniv, Moshe

Book ID
110031193
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
397 KB
Volume
24
Category
Article
ISSN
0261-4189

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## Abstract Many mammalian SWI/SNF complexes use Brahma‐related gene 1 (Brg1) as a catalytic subunit to remodel nucleosomes for transcription regulation. In several mesenchymal cells and tissues, expression of a defective Brg1 protein negates the normal activity of the SWI/SNF complex and delays or