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Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex

✍ Scribed by Hu, Keping; Nan, Xinsheng; Bird, Adrian; Wang, Weidong

Book ID
109916822
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
837 KB
Volume
38
Category
Article
ISSN
1061-4036

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## Abstract Many mammalian SWI/SNF complexes use Brahma‐related gene 1 (Brg1) as a catalytic subunit to remodel nucleosomes for transcription regulation. In several mesenchymal cells and tissues, expression of a defective Brg1 protein negates the normal activity of the SWI/SNF complex and delays or