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PS2-067. The SWI/SNF chromatin remodeling complex is essential for early B cell development

✍ Scribed by Rho H. Seong

Book ID: 116400285
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 39 KB
Volume: 56
Category: Article
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2011.07.229

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## Abstract Many mammalian SWI/SNF complexes use Brahma‐related gene 1 (Brg1) as a catalytic subunit to remodel nucleosomes for transcription regulation. In several mesenchymal cells and tissues, expression of a defective Brg1 protein negates the normal activity of the SWI/SNF complex and delays or

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