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The Swi/Snf chromatin remodeling complex is essential for hyphal development in Candida albicans

✍ Scribed by Xuming Mao; Fang Cao; Xinyi Nie; Haoping Liu; Jiangye Chen

Book ID: 116466599
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 393 KB
Volume: 580
Category: Article
ISSN: 0014-5793
DOI: 10.1016/j.febslet.2006.04.009

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## Abstract Many mammalian SWI/SNF complexes use Brahma‐related gene 1 (Brg1) as a catalytic subunit to remodel nucleosomes for transcription regulation. In several mesenchymal cells and tissues, expression of a defective Brg1 protein negates the normal activity of the SWI/SNF complex and delays or