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The suppression of experimental allergic encephalomyelitis in Lewis rats by treatment with myelin basic protein-cell conjugates

✍ Scribed by Rachel M. McKenna; Brian G. Carter; Jean A. Paterson; Alec H. Sehon


Book ID
113132665
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
888 KB
Volume
81
Category
Article
ISSN
0008-8749

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## Abstract The highly encephalitogenic guinea pig peptide 68‐88 has been used to develop an effective and reproducible model of protection in the Lewis rat. Doses as low as 0.1 nmol of peptide protected 70% of rats when injected intraperitoneally six and four weeks prior to challenge with 0.05 nmo