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Suppression of experimental allergic encephalomyelitis in the Lewis rat, by administration of an acylated synthetic peptide of myelin basic protein

โœ Scribed by Joanne St. Louis; Edwin L Chan; Bhagirath Singh; Gill H Strejan


Book ID
117337363
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
337 KB
Volume
73
Category
Article
ISSN
0165-5728

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## Abstract The highly encephalitogenic guinea pig peptide 68โ€88 has been used to develop an effective and reproducible model of protection in the Lewis rat. Doses as low as 0.1 nmol of peptide protected 70% of rats when injected intraperitoneally six and four weeks prior to challenge with 0.05 nmo