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Combined Nasal Administration of Encephalitogenic Myelin Basic Protein Peptide 68–86 and IL-10 Suppressed Incipient Experimental Allergic Encephalomyelitis in Lewis Rats

✍ Scribed by Ling-Yun Xu; Jian-She Yang; Yu-Min Huang; Michael Levi; Hans Link; Bao-Guo Xiao


Book ID
118768380
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
108 KB
Volume
96
Category
Article
ISSN
1090-2341

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✍ Dr. Frank C.-H. Chou; C.-H. Jen Chou; Robert B. Fritz; Robert F. Kibler 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 374 KB 👁 1 views

## Abstract The highly encephalitogenic guinea pig peptide 68‐88 has been used to develop an effective and reproducible model of protection in the Lewis rat. Doses as low as 0.1 nmol of peptide protected 70% of rats when injected intraperitoneally six and four weeks prior to challenge with 0.05 nmo