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Mechanisms of recovery from experimental allergic encephalomyelitis induced with myelin basic protein peptide 68–86 in Lewis rats: a role for dendritic cells in inducing apoptosis of CD4+ T cells

✍ Scribed by Bao-Guo Xiao; Yu-Min Huang; Ling-Yun Xu; Mikio Ishikawa; Hans Link


Book ID
114138852
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
963 KB
Volume
97
Category
Article
ISSN
0165-5728

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Studies from our laboratory have shown that region 69-84 (synthetic peptide S49S) of myelin basic protein (MBP) defines an encephalitogenic sequence for experimental allergic encephalomyelitis (EAE) in Lewis rats. The most potent EAE inducers are the guinea pig MBP (Gp-MBP) and region 69-84, known a