𝔖 Bobbio Scriptorium
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The structures of trichodiol and trichodiene

✍ Scribed by S. Nozoe; Y. Machida


Book ID
104204520
Publisher
Elsevier Science
Year
1972
Tongue
French
Weight
505 KB
Volume
28
Category
Article
ISSN
0040-4020

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πŸ“œ SIMILAR VOLUMES


Structure of trichodiene
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## Abstract The synthesis of radiolabelled trichodiene with ^14^C at the olefinic methyl (C‐16) is described. The isotope was introduced using a ^14^C‐Wittig reagent prepared __in situ__ from triphenyl phosphine and ^14^C‐methyliodide.

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A highly regio-and stereoselective synthesis of the sesquiterpenoid trichediene is reported. The approach requires only nine steps starting with a [2+2] photoaddition and employs the free radical fragmentation of an "external" cyclobutane bond in a key step.