Structure of trichodiene
β Scribed by Shigeo Nozoe; Yoshimasa Machida
- Book ID
- 104249118
- Publisher
- Elsevier Science
- Year
- 1970
- Tongue
- French
- Weight
- 183 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A route to the total synthesis of the title compound is described. The key step involves the [3,3] sigmatropic of the silyl keteneacetal derived from an allylic P-ketoester. The potential application of this protocol to the construction of the higher trichothecenes is also discussed.
Three new natural products were isolated from Fumrium spp, one apotricho~ aad two oxygenated derivatives of trichodiene. The apotrichothecene was a precu&r to apotrichcdiol and saa~buci-IIOI. Apotrichothecenes were for a long time considered to be the products of the trichothecenes under acidic con
## Abstract The synthesis of radiolabelled trichodiene with ^14^C at the olefinic methyl (Cβ16) is described. The isotope was introduced using a ^14^CβWittig reagent prepared __in situ__ from triphenyl phosphine and ^14^Cβmethyliodide.