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The structure of anhydro erythromycin a carbonate

✍ Scribed by A. Hempel; M. Bogucka-Ledóchowska; Z. Dauter; E. Borowski; Z. Kosturkiewicz

Publisher: Elsevier Science
Year: 1975
Tongue: French
Weight: 250 KB
Volume: 16
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)72208-8

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✦ Synopsis

Among the semisynthetlo derivative8 of an importent antibiotio, erythrunytin A, Its cyclic carbonate exhibit8 the unique property of being more active against becteria than the parent antibiotic l,B . In the hypothetical struoture of the canpound pO8tUlated by Eli Lilly group, the substitution by carbonate moiety occurred at 9 and 11 oarbon atams of the macrolide ring'.

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