The status of the p53 gene in human hepatocellular carcinoma cells influences the responses of cell cycle-associated gene (Cyclin A, CDC2, RB, p21) by gene transfer of p53
โ Scribed by Nakayama, Daiju; Magami, Yasushi; Furukawa, Masaya; Moriyasu, Fuminori; Nikaido, Toshio; Sakai, Toshiyuki
- Book ID
- 124147256
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 188 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0016-5085
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Mutation of the p53 gene is found in about one third of astrocytic brain tumors, and expansion of tumor cell clones containing mutant p53 has been implicated in astrocytic tumor progression. However, admixture of normal cells in astrocytic tumor specimens limits the power of traditional studies of t
Genes encoding cdkl (~34'~''), cyclin A, cyclin B, and the tumor suppressor gene Rb are fundamental regulators of cell cycle progression which associate as a complex with the transcription factor E2F. Expression of many of these proteins has previously been shown to be repressed by okadaic acid, a s