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The speckling domain of the Wilms tumor suppressor WT1 overlaps with the transcriptional repression domain

✍ Scribed by Ute Herzer; Bertram Lutz; Kristina Hartmann; Christoph Englert

Book ID: 117102878
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 305 KB
Volume: 494
Category: Article
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(01)02313-4

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## Abstract This study reports on the evaluation of the Wilms tumor suppressor gene __WT1__ in 14 endometrial carcinomas. Despite the fact that several endometrial carcinomas were shown to express __WT1__, we were unable to demonstrate mutations in the __MT1__ zinc finger region, suggesting that __