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Analysis of the wilms tumor suppressor gene WT1 in endometrial carcinoma

✍ Scribed by Raymond Rackley; Graham Casey; Xiao-Ian Zhao; David W. Miller; Bryan R. G. Williams; Dr. Max J. Coppes

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
243 KB
Volume
14
Category
Article
ISSN
1045-2257

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✦ Synopsis

Abstract

This study reports on the evaluation of the Wilms tumor suppressor gene WT1 in 14 endometrial carcinomas. Despite the fact that several endometrial carcinomas were shown to express WT1, we were unable to demonstrate mutations in the MT1 zinc finger region, suggesting that WT1 does not play a prominent role in the etiology of this malignancy.

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