The Wilms Tumor Suppressor WT1 Encodes a Transcriptional Activator of amphiregulin
β Scribed by Sean Bong Lee; Karen Huang; Rachel Palmer; Vivi B Truong; Doris Herzlinger; Kathryn A Kolquist; Jenise Wong; Charles Paulding; Seung Kew Yoon; William Gerald; Jonathan D Oliner; Daniel A Haber
- Book ID
- 117267117
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 425 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0092-8674
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## Abstract This study reports on the evaluation of the Wilms tumor suppressor gene __WT1__ in 14 endometrial carcinomas. Despite the fact that several endometrial carcinomas were shown to express __WT1__, we were unable to demonstrate mutations in the __MT1__ zinc finger region, suggesting that __
## Abstract Dmp1 (Dmtf1) encodes a Mybβlike transcription factor implicated in tumor suppression through direct activation of the Arfβp53 pathway. The human __DMP1__ gene is frequently deleted in nonβsmall cell lung cancers, especially those that retain wildβtype __INK4a/ARF__ and/or __p53__. To id