The Wilms’ tumor suppressor WT1 is associated with melanoma proliferation
✍ Scribed by Nicole Wagner; John Panelos; Daniela Massi; Kay-Dietrich Wagner
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 608 KB
- Volume
- 455
- Category
- Article
- ISSN
- 0031-6768
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## Abstract This study reports on the evaluation of the Wilms tumor suppressor gene __WT1__ in 14 endometrial carcinomas. Despite the fact that several endometrial carcinomas were shown to express __WT1__, we were unable to demonstrate mutations in the __MT1__ zinc finger region, suggesting that __
The expression of the Wilms tumor suppressor gene WT1 is largely restricted to elements of the developing urogenital system. In the fetal kidney, WT1 transcripts are present at low levels in the condensing mesenchyme and at much higher levels in differentiating glomerular epithelium and are not dete