## Abstract The solidβstate catalytic hydrogenation (SCH) of unsaturated precursor compound and the highβtemperature solidβstate catalytic isotope exchange (HSCIE) showed that the total incorporation of isotope and its distribution between the Ξ±βand Ξ²βpositions of the alanine molecule can be modifi
The solid-state catalytic synthesis of tritium labeled amino acids, peptides and proteins
β Scribed by Yu. A. Zolotarev; E. M. Dorokhova; V. N. Nezavibatko; Yu. A. Borisov; S. G. Rosenberg; G. A. Velikodvorskaia; L. V. Neumivakin; V. V. Zverlov; N. F. Myasoedov
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 832 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0939-4451
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π SIMILAR VOLUMES
This is the first of five books in the *Amino Acids, Peptides and Proteins in Organic Synthesis* series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino
Optically pure L-valine was labelled with tritium by the Wilzbach method. Only 4 of the activity of the radiochemically pure valine was found in D-valine. This figure was determined by reverse isotope dilution. The suitability of this method for valine was tested, wich good results, with DL-valine
## Abstract The results of a study of. the solidβstate catalytic hydrogenation and the synthesis of tritium labelled native heterocyclic bases are presented. The effect of different palladium catalysts and reaction conditions on yield and molar radioactivity of final compounds was investigated. For
Optically pure amino-acids were labelled with tritium by the Wilzbach method. The percentage of radioactivity found in the opposite enantiomer was determined by reverse dilution analysis. After tritiation of L-phenylalanine, D-phenylalanine, L-tyrosine, L-proline, D-proline, L-glutamic acid and L-al