Optically pure amino-acids were labelled with tritium by the Wilzbach method. The percentage of radioactivity found in the opposite enantiomer was determined by reverse dilution analysis. After tritiation of L-phenylalanine, D-phenylalanine, L-tyrosine, L-proline, D-proline, L-glutamic acid and L-al
Tritium labelling of amino-acids and peptides by the Wilzbach method
β Scribed by J. H. Parmentier
- Publisher
- John Wiley and Sons
- Year
- 1965
- Tongue
- French
- Weight
- 369 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0022-2135
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β¦ Synopsis
Optically pure L-valine was labelled with tritium by the Wilzbach method. Only 4 of the activity of the radiochemically pure valine was found in D-valine. This figure was determined by reverse isotope dilution.
The suitability of this method for valine was tested, wich good results, with DL-valine also labelled by the Wilzbach method.
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This is the first of five books in the *Amino Acids, Peptides and Proteins in Organic Synthesis* series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino