✦ LIBER ✦

The solid phase synthesis of oligonucleotides containing a 3′-peptide moiety

✍ Scribed by Jim Haralambidis; Lucy Duncan; Geoffrey W. Tregear

Publisher: Elsevier Science
Year: 1987
Tongue: French
Weight: 243 KB
Volume: 28
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)95628-4

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Solid phase synthesis of oligonucleotide

Solid phase synthesis of oligonucleotides containing 3′-thiothymidine

✍ Richard Cosstick; Joseph S. Vyle 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 254 KB

Summarv-A 5'-O-monomethoxytritylthymidine-3'-S-thiophosphoramidite (3) has been used to prepare oligodeoxynucleotides containing 3'-thiothymidine on a solid phase support. The intermediate thiophosphites are most efficiently oxidised using tetrabutylammonium periodate. Polynucleotide analogues conta

Novel solid phase synthesis supports for

Novel solid phase synthesis supports for the preparation of oligonucleotides containing 3′-alkyl amines.

✍ Dustin L. McMinn; Marc M. Greenberg 📂 Article 📅 1996 🏛 Elsevier Science 🌐 French ⚖ 576 KB

Stepwise Solid-Phase Synthesis of Peptid

Stepwise Solid-Phase Synthesis of Peptide-Oligonucleotide Conjugates on New Solid Supports

✍ Maxim Antopolsky; Alex Azhayev 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 German ⚖ 139 KB 👁 2 views

Solid phase synthesis of peptides contai

Solid phase synthesis of peptides containing novel L-phenylalanine derivatives substituted with vicinal tricarbonyl moieties

✍ Heinz Fretz 📂 Article 📅 1996 🏛 Elsevier Science 🌐 French ⚖ 204 KB

Stepwise solid-phase synthesis of peptid

Stepwise solid-phase synthesis of peptide–oligonucleotide phosphorothioate conjugates employing Fmoc peptide chemistry

✍ Maxim Antopolsky; Alex Azhayev 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 86 KB

A straightforward stepwise method for the preparation of peptide-oligonucleotide phosphorothioate conjugates, was developed, based on the highly efficient Fmoc peptide solid phase synthesis, followed by oligonucleotide phosphorothiate chain assembly. The three conjugates synthesized contained 15-or

Towards a general method for the stepwis

Towards a general method for the stepwise solid-phase synthesis of peptide–oligonucleotide conjugates

✍ Maxim Antopolsky; Elena Azhayeva; Unni Tengvall; Alex Azhayev 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 74 KB

Three peptide-oligonucleotide phosphorothioate hybrids were synthesized using a new approach for stepwise solidphase synthesis of conjugates. This method utilizes commercially available N a -Fmoc amino acids for peptide synthesis and a new solid support. Three specific modifications of the solid-pha