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The size of duplication does not add to the prognostic significance of FLT3 internal tandem duplication in acute myeloid leukemia patients

✍ Scribed by Ponziani, V; Gianfaldoni, G; Mannelli, F; Leoni, F; Ciolli, S; Guglielmelli, P; Antonioli, E; Longo, G; Bosi, A; Vannucchi, A M

Book ID
110056884
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
90 KB
Volume
20
Category
Article
ISSN
0887-6924

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## Background. Recently, an internal tandem duplication of the FLT3 gene (FLT3/ITD) was found in 20% of adult cases of acute myelogenous leukemia (AML), and this length abnormality was suggested to be associated with leukemic progression. Procedure. We examined the mRNA expression of the FLT3 gene